• Legume Consumption and Cardiometabolic Health | …

    Legume consumption and CHD risk. The association between legume consumption and risk of CHD has been analyzed in several prospective studies (Supplemental Table 2).A meta-analysis of 5 prospective studies involving 6514 ischemic heart disease cases found a 14% lower risk of total ischemic heart disease in the highest legume consumption category compared with the lowest …Advancing Scientific Understanding of the Global Methane ...1 The Role of Atmospheric CH 4 in Achieving Global Climate Targets. Methane (CH 4) is the second most important human-made ("anthropogenic") greenhouse gas after carbon dioxide (CO 2) and accounts for at least 25% of the anthropogenic radiative forcing of warming agents since preindustrial times (including indirect effects due to atmospheric chemistry) (Etminan et al., …

  • Aqueous pKa prediction for tautomerizable compounds …

    2020-2-12 · 1,3-CHD is a fragment prevalent to both agrochemically and pharmaceutically active compounds in use today. Alloxydim (Fig. 1b(i)) is currently used as a selective systemic herbicide for post ...Selenium and human health - The Lancet2012-2-29 · Selenium is incorporated into selenoproteins that have a wide range of pleiotropic effects, ranging from antioxidant and anti-inflammatory effects to the production of active thyroid hormone. In the past 10 years, the discovery of …

  • Lipids and the endothelium | Cardiovascular Research ...

    The normal endothelium is characterised by the production of a number of molecules which affect the contractile state of adjacent myocytes and the behavior of formed elements within the blood stream, and by the absence of cell surface adhesion molecules. In addition, endothelial cells are important modulators of coagulation and fibrinolysis u Cormand - UB2020-1-26 · Beltrán-Valero de Bernabé D, Currier S, Steinbrecher A, Celli J, van Beusekom E, Kayserili H, Merlini L, Chitayat D, Dobyns WB, Cormand B, Lehesjoki AE, Cruces J, Voit T, Walsh CA, van Bokhoven H, Brunner HG. Mutations in the O-mannosyltransferase gen POMT1 give rise to the severe neuronal migration disorder Walker-Warburg syndrome.

  • Receptor-mediated Catabolism of Low Density …

    2014-1-30 · 4 60 M 106 148 CHD 267±4 292±16 138±9 5 53 M 131 182 CHD 192±3 265±11 108±4 6 48 M 105 142 CVD 228±7 374±15 79±6 ° Averages of eight determinations (mean±SEM). CHD,coronary heart disease; CVD,carotid vascular disease. 80% ofLowDensity Lipoprotein Catabolism is Receptor-Mediated 951Association between circulating oxidized low-density ...2017-6-25 · To date, three monoclonal antibodies have been developed for determination of circulating ox-LDL by enzyme linked immunosorbent assay (ELISA): ox-LDL-4E6, 11 ox-LDL-E06, 12 and ox-LDL-DLH3 antibody. 13 Ox-LDL-4E6 was the first to be established and widely used. It can directly recognize the epitope that is generated after modification of lysine residues in …

  • Pathophysiology of Coronary Artery Disease | Circulation

    2005-6-28 · Abstract. During the past decade, our understanding of the pathophysiology of coronary artery disease (CAD) has undergone a remarkable evolution. We review here how these advances have altered our concepts of …Association between circulating oxidized low-density ...2017-6-25 · Introduction. Atherosclerosis is a chronic, progressive pathological process that involves vascular endothelial injury, lipid infiltration, macrophage activation, vascular smooth muscle cell proliferation, thrombosis, and inflammatory immune response, eventually leading to coronary heart disease (CHD), ischemic stroke, and other atherosclerotic cardiovascular …

  • Case Definitions for Use in Population‐Based Surveillance ...

    Many definitions of periodontitis have been used in the literature for population‐based studies, but there is no accepted standard. In early epidemiologic studies, the two major periodontal diseases, gingivitis and periodontitis, were combined and considered to be a continuum.Lipids and the endothelium | Cardiovascular Research ...The normal endothelium is characterised by the production of a number of molecules which affect the contractile state of adjacent myocytes and the behavior of formed elements within the blood stream, and by the absence of cell surface adhesion molecules. In addition, endothelial cells are important modulators of coagulation and fibrinolysis.

  • Omega-6 vegetable oils as a driver of coronary heart ...

    2022-1-7 · In 1984, both Steinbrecher et al and Morel et al discov-ered that endothelial cells can oxidise LDL and that this process involves lipid peroxidation.28 29 Oxidised LDL was found to be atherogenic and toxic to endothelial cells. In 1990, Miyazawa et al confirmed elevated levels of hydroperoxides from linoleic acid in human LDL,30Vitamin C in human health and disease is still a mystery ...2003-8-21 · Steinbrecher UP, Zhang H, Lougheed M: Role of oxidative modified LDL in atherosclerosis. Free Rad Biol Med. 1990, 9: 155-168. 10.1016/0891-5849(90)90119-4. CAS PubMed Google Scholar 38. Frei B: Vitamin C as an antiatherogen: mechanism of action. In Vitamin C in Health and disease.

  • Selenium and human health

    2012-2-29 · Selenium is incorporated into selenoproteins that have a wide range of pleiotropic effects, ranging from antioxidant and anti-inflammatory effects to the production of active thyroid hormone. In the past 10 years, the discovery of …Aqueous pKa prediction for tautomerizable compounds …2020-2-12 · 1,3-CHD is a fragment prevalent to both agrochemically and pharmaceutically active compounds in use today. Alloxydim (Fig. 1b(i)) is currently used as a selective systemic herbicide for post ...

  • Comparison of Glucosylated Low Density Methylated ...

    2021-12-31 · This suggests that CHD-LDL overestimates theamountof LDLdegradedby recep-tor-independent pathways, perhaps because the CHD Dr. Steinbrecher is a Fellow of the Medical Research Councilof Canada,andDr. Kesaniemiis a Visiting Scientist from the 2nd Department of Medicine, University of Hel-sinki, Finland. Address all correspondence to Dr. Stein .. parison of glucosylated low density lipoprotein with ...Steinbrecher UP, Witztum JL, Kesaniemi YA, Elam RL. ... This suggests that CHD-LDL overestimates the amount of LDL degraded by receptor-independent pathways, perhaps because the CHD modification is spontaneously reversible. The present studies indicate that GLC-LDL is a useful tracer of receptor-independent LDL catabolism in animals.

  • Comparison of glucosylated low density lipoprotein with ...

    1983-4-1 · The FCR of CHD-LDL was greater than that of the other modified LDL, and it varied depending on how soon after preparation the CHD-LDL was injected: when used within 2 h of preparation, the mean FCR was 0.044 +/- 0.007 h-1 (n = 4); when used after overnight dialysis at 4 degrees C, the mean FCR was 0.082 +/- 0.03 h-1 (n = 4).Atherosclerosis and the Cholesterol Theory: A ReappraisalAtherosclerosis is the precedent to ischemic heart disease, which may lead to angina, myocardial infarct, or heart failure; or to ischemic cerebrovascular disease, which may lead to stroke. The prevailing belief underlying conventional …

  • Advancing Scientific Understanding of the Global Methane ...

    1 The Role of Atmospheric CH 4 in Achieving Global Climate Targets. Methane (CH 4) is the second most important human-made ("anthropogenic") greenhouse gas after carbon dioxide (CO 2) and accounts for at least 25% of the anthropogenic radiative forcing of warming agents since preindustrial times (including indirect effects due to atmospheric chemistry) (Etminan et al., …Search | Urology News2014-3-1 · Bladder pain syndrome / interstitial cystitis (BPS/IC) is a chronic, multifactorial and relapsing condition. Aetiology includes: inflammation, allergic, neuropathic, auto immune, vascular factors, etc. This study from Taiwan aimed to investigate the risk of …

  • Myeloperoxidase and Cardiovascular Disease ...

    Myeloperoxidase (MPO) is a leukocyte-derived enzyme that catalyzes the formation of a number of reactive oxidant species. In addition to being an integral component of the innate immune response, evidence has emerged that MPO …chd_psx_misc directory listing - Internet ArchiveL''ile LEGO 2 - La Revanche de Cassbrik (France) d: 25-Oct-2020 16:53: 147.3M: LEGO Eiland 2 - De Wraak van Dondersteen (Netherlands) d: 25-Oct-2020 17:22: 153.7M: LEGO Insel 2 - Der Steinbrecher kehrt zurueck (Germany) d: 25-Oct-2020 17:23: 147.4M: LEGO Island 2 - The Brickster''s Revenge (Norway) d: 30-Nov-2020 13:32: 146.3M

  • Receptor-mediated Catabolism of Low Density …

    2014-1-30 · 4 60 M 106 148 CHD 267±4 292±16 138±9 5 53 M 131 182 CHD 192±3 265±11 108±4 6 48 M 105 142 CVD 228±7 374±15 79±6 ° Averages of eight determinations (mean±SEM). CHD,coronary heart disease; CVD,carotid vascular disease. 80% ofLowDensity Lipoprotein Catabolism is Receptor-Mediated 951Myeloid Tribbles 1 induces early atherosclerosis via ...Atherosclerosis, a progressive disease of arterial blood vessels and the main underlying cause of stroke, myocardial infarction, and cardiac death (), is initiated by the conversion of plaque macrophages to cholesterol-laden foam cells in the arterial intima () the early-stage atherosclerotic plaque, this transformation is induced by the uptake of both low density …

  • Risk of angina pectoris and plasma concentrations of ...

    1991-1-5 · The Lancet ORIGINAL ARTICLES Risk of angina pectoris and plasma concentrations of vitamins A, C, and E and carotene R.A. Riemersma PhD * a * Correspondence to Dr R. A. Riemersma, Cardiovascular Research Unit, University of Edinburgh, George Square, Edinburgh EH8 9XF, UK Prof D.A. Wood MRCP 1 a 1 Present address: Preventive Cardiology, Medicine …Advancing Scientific Understanding of the Global Methane ...1 The Role of Atmospheric CH 4 in Achieving Global Climate Targets. Methane (CH 4) is the second most important human-made ("anthropogenic") greenhouse gas after carbon dioxide (CO 2) and accounts for at least 25% of the anthropogenic radiative forcing of warming agents since preindustrial times (including indirect effects due to atmospheric chemistry) (Etminan et al., …

  • Previously Funded SSRP Projects

    Previously Funded SSRP Projects. Breast Cancer, breast reconstruction, radiation, machine learning, prediction model. Some projects were adversely affected by the COVID-19 pandemic, and could not be fully completed due to in-person research restrictions throughout the summer.Thematic review series: The Pathogenesis of ...For more than two decades, there has been continuing evidence of lipid oxidation playing a central role in atherogenesis. The oxidation hypothesis of atherogenesis has evolved to focus on specific proinflammatory oxidized phospholipids that result from the oxidation of LDL phospholipids containing arachidonic acid and that are recognized by the innate immune …

  • Legume Consumption and Cardiometabolic Health | …

    Legume consumption and CHD risk. The association between legume consumption and risk of CHD has been analyzed in several prospective studies (Supplemental Table 2).A meta-analysis of 5 prospective studies involving 6514 ischemic heart disease cases found a 14% lower risk of total ischemic heart disease in the highest legume consumption category compared with the lowest …JCI - Scavenging new insights into atherogenesisIn Japan, 2–3% of the general population is deficient for CD36, but, interestingly, 12% of Japanese patients with coronary heart disease (CHD) carry this deficiency . Hence, loss of CD36 function is associated with cardiovascular diseases, and interference with CD36 function appears more likely to cause than to inhibit CHD.

  • Consumption of meat and dairy products in China: a …

    2016-6-23 · Therefore, meat consumption had been identified as a dietary risk factor for CHD (Reference Denke 5, Reference Hu, Stampfer and Manson 6), obesity (Reference Vergnaud, Norat and Romaguera 7), diabetes (Reference Steinbrecher, Erber and Grandinetti 8), colorectal cancer (9) and stroke (Reference Micha, Wallace and Mozaffarian 10).Oxidized Low Density Lipoprotein, Statin Therapy and ...2018-9-25 · prevention of CHD (D.Y. Li et al., 2001). Previous studies have detected some efficacy in reducing the circulating oxLDL levels, but whether this effect is due to the reduction of LDL or is an independent, pleiotropic phenomenon remains a matter of controversy (Kwak & Mach, 2001; Robinson et al., 2005).

  • Oxidized Low Density Lipoprotein, Statin Therapy and ...

    2018-9-25 · prevention of CHD (D.Y. Li et al., 2001). Previous studies have detected some efficacy in reducing the circulating oxLDL levels, but whether this effect is due to the reduction of LDL or is an independent, pleiotropic phenomenon remains a matter of controversy (Kwak & Mach, 2001; Robinson et al., 2005) nsumption of meat and dairy products in China: a …2016-6-23 · Therefore, meat consumption had been identified as a dietary risk factor for CHD (Reference Denke 5, Reference Hu, Stampfer and Manson 6), obesity (Reference Vergnaud, Norat and Romaguera 7), diabetes (Reference Steinbrecher, Erber and Grandinetti 8), colorectal cancer (9) and stroke (Reference Micha, Wallace and Mozaffarian 10).

  • psx-chd-roms-l directory listing

    2020-8-4 · L''ile LEGO 2 - La Revanche de Cassbrik (France) d: 04-Aug-2020 06:46: 147.3M: LEGO Eiland 2 - De Wraak van Dondersteen (Netherlands) d: 04-Aug-2020 06:34: 153.7M: LEGO Insel 2 - Der Steinbrecher kehrt zurueck (Germany) d: 04-Aug-2020 06:34: 147.4M: LEGO Island 2 - The Brickster''s Revenge (Europe) d: 04-Aug-2020 06:34: 148.4MSelenium and human health - The Lancet2012-2-29 · Selenium is incorporated into selenoproteins that have a wide range of pleiotropic effects, ranging from antioxidant and anti-inflammatory effects to the production of active thyroid hormone. In the past 10 years, the discovery of …

  • (PDF) Paraoxonase (PON1) & coronary heart disease

    In seeking an explanation of the inverse relationship between serum high density lipoprotein (HDL) concentration and coronary heart disease (CHD) …Myeloperoxidase and Cardiovascular Disease ...Myeloperoxidase (MPO) is a leukocyte-derived enzyme that catalyzes the formation of a number of reactive oxidant species. In addition to being an integral component of the innate immune response, evidence has emerged that MPO …

  • Pathophysiology of Coronary Artery Disease | Circulation

    2005-6-28 · Abstract. During the past decade, our understanding of the pathophysiology of coronary artery disease (CAD) has undergone a remarkable evolution. We review here how these advances have altered our concepts of …(PDF) Paraoxonase (PON1) & coronary heart diseaseIn view of the current theory that oxidative modification of LDL is an important element in atherogenesis, this suggests another potential mechanism by which HDL might impede the development of CHD.

  • Is plasma oxidized low-density lipoprotein, measured with ...

    2006-8-17 · Objectives Our aim was to examine whether circulating oxidized low-density lipoprotein (oxLDL) is a predictor of coronary heart disease (CHD) independent of lipid markers and to compare oxLDL, apolipoprotein B100 (apoB), and total cholesterol (TC)/high-density lipoprotein-cholesterol (HDL-C) ratio as predictors of CHD.Receptor-mediated Catabolism of Low Density …2014-1-30 · 4 60 M 106 148 CHD 267±4 292±16 138±9 5 53 M 131 182 CHD 192±3 265±11 108±4 6 48 M 105 142 CVD 228±7 374±15 79±6 ° Averages of eight determinations (mean±SEM). CHD,coronary heart disease; CVD,carotid vascular disease. 80% ofLowDensity Lipoprotein Catabolism is Receptor-Mediated 951

  • Thematic review series: The Pathogenesis of ...

    For more than two decades, there has been continuing evidence of lipid oxidation playing a central role in atherogenesis. The oxidation hypothesis of atherogenesis has evolved to focus on specific proinflammatory oxidized phospholipids that result from the oxidation of LDL phospholipids containing arachidonic acid and that are recognized by the innate immune …Case Definitions for Use in Population‐Based Surveillance ...Many definitions of periodontitis have been used in the literature for population‐based studies, but there is no accepted standard. In early epidemiologic studies, the two major periodontal diseases, gingivitis and periodontitis, were combined and considered to be a continuum.

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